How vaccine works on coronavirus?
Officially known now as copy 19 the total number of confirmed the cases in China has surpassed 70,000 the desktop now reached over 1700 well over 11,000 people have recovered here are the latest developments on the virus the majority of confirmed cases in China are in hebei province in fact 70% are in the provincial capital Wuhan where the outbreak began on Monday newly confirmed cases outside who bei were down 90 percent compared to their peak on February 3rd.
A hospital in Wuhan has completed autopsies on the bodies of two patients who died of the virus medical researchers are now reviewing the pathogen reports Chinese Halla thority say the country has taken effective measures to contain the outbreak of the virus jiggity beam Stan Shiva soon father though the disease is new it is preventable and curable the daily new cases outside who may have dropped four consecutive 13 days these signal that the measures we took are very effective.
I believe we will summarize a set of strategies and led us to increase the recovery rate not only China but also the international community can take advantage of those experiences meanwhile in China more businesses have reopened a freight train has left jeong-ja for central asia marking the resumption of the china europe freight trains in the city. you and now I'm joined by Professor gelling Chi from the department of the basic and medical sciences from the School of Medicine with two moi University professor John thank you so much for sharing your precious time out of your very very busy schedule recently how are you supporting the frontline and meanwhile how are you doing your research regarding the antibody and vaccines over the last several years in my group and then dr. waz and showers group at my university we are we have been focused on research activity to understand how viruses getting to cells by understanding our processes we could develop a good drugs and antibodies and vaccines to start that process so these are our understanding of this process.
we are now using the genetic and recombination technologies develop several vaccine strategies hopefully by using those strategies and immunize individuals we are able to induce the antibody responses able to stop the viral infection so that actually the prime purpose of our current research on campus on the other hand uses cognitive processes we also develop a crucial in illogical testing help the frontline physicians to evaluate the plasma and blood amiri activity so they could use as a surrogate marker to evaluate the potential effectiveness of the plasma infusion that is to treat most severe patient at frontline talking about plasma this is the key word or recently in terms of therapeutic treatment now that process of being used in many cases earlier in treating different kinds of diseases
but,
whether do we know or not this is likely to work according to the latest the situation we have 11 so-called successful cases within 24 hours but is that big enough to support this argument this is a very important area of investigation for this particular carnivals we are not certain whether or to what extent is a effective so that require a systematic and comprehensive research that's why we are providing the support to evaluate the new status of that plasma try to correlate that with the effectiveness of treatment in fact this concept of using plasma to treat infectious diseases back to almost a hundred years ago and when the German scientist ambulant Aran developed the antiserum of plasma against the toughest area so he actually the first winner of normal price in his industry and then and then in medicine but because of his idea and concept develop of equivalent plasma treatment for infectious diseases in fact during the outbreak of many other more infection including Ebola and then highly pathogenic influenza some editors experiment has been conducted in human
but the size and also the conclusive conclusion have not been wished yeah so given the size of the severe infected patients now in China we are have it is unique and then good opportunity to address that in a most a scientific manner so we could reach a firm conclusion based on those important studies professor Jung now we understand more than 10,000 people according to the latest information recovered about the question really is what is the ratio professor there's a crucial issue like this about you know how much a plasma being used can be for the treatment of how many patients or vice versa do we know is there any statistics that
we
have collected whether this is going to be a resource effective this is a really great question because if we depend on those natural reasons resources work will be very limited but at present given what we have practiced over the years for a donor if you are a convalescent you can cover patients you are encouraged to donate plasma blood for the severe for treatment of severe patient for each one donation someone could donate several hundreds of meals and then you could use that and after certain treatments and then of this plasma samples to remove some potential harmful materials and to activate viruses those samples can be infused directly into patients may be with ranging from two hundred to two more meals but as I said those are dependent on the natural resources of convalescent patients and quite limited that's why in our research field we have been collaborating to the partners in Beijing in change and many many other places try to isolate those antibodies from the recover patients so we could use molecular current method and also production facility to manufacturers kilogram we use tons of those antibodies that will overcome the sharpish on its means from convalescent serum on patients there's another thing regarding plasma because we had earlier public health emergencies or accidents when people donate their blood and they have the plasma separated from the blood cells and eventually they have the once again there the rest of the blood coming back to their body just is going to help those who have donated the blood but eventually became a public health accident we remember that we were well are concerning them AIDS patients years ago so a professor Jeong at this critical moment everybody's rushing for solutions how important it is that we take care of different size of the same issue those are really good points we when the immersion happens we tend to be over overly act and then during this roughness we may make some mistakes but we have to be very very vigilant about safety first safety safety safety once we have collected the collagen serum or plasma condensation those who are not will have to be treated properly according to the protocol that has been used in the field for years so safety precautions is is must so given what we have in conducting and knowing all these years the safety procedure has already been in place and I am sure that many of the hospitals and physicians are conducting.
those trials put the safety first on top of the list but you know as you may know call me the 19 is a very infectious disease we have seen it's easily be infectious from one to the other so medical workers at different departments of the hospital I have to protect themselves because they also need to protect their patients because once they are infected they're going to spread it to the others too so how to keep that balance on the one hand you want to make sure there's medical support to the people with long-term disease but on the other hand you want to make sure all the medical workers as well as patients seeking pay is seeking treatment in the hospitals can be saved this is quite a dilemma absolutely I think that this emergency cases in particular we are not understanding or we don't understand fully how this virus translates so viciously so everybody has to be in precaution to prevent themselves and prevent from their patients to be infected this is entirely new viruses to us and we don't know how it is in fact so it is a better for all of us to be to be on guard and to be fully cautious and protect themselves and then to minimize the chance of transmission ,
A hospital in Wuhan has completed autopsies on the bodies of two patients who died of the virus medical researchers are now reviewing the pathogen reports Chinese Halla thority say the country has taken effective measures to contain the outbreak of the virus jiggity beam Stan Shiva soon father though the disease is new it is preventable and curable the daily new cases outside who may have dropped four consecutive 13 days these signal that the measures we took are very effective.
I believe we will summarize a set of strategies and led us to increase the recovery rate not only China but also the international community can take advantage of those experiences meanwhile in China more businesses have reopened a freight train has left jeong-ja for central asia marking the resumption of the china europe freight trains in the city. you and now I'm joined by Professor gelling Chi from the department of the basic and medical sciences from the School of Medicine with two moi University professor John thank you so much for sharing your precious time out of your very very busy schedule recently how are you supporting the frontline and meanwhile how are you doing your research regarding the antibody and vaccines over the last several years in my group and then dr. waz and showers group at my university we are we have been focused on research activity to understand how viruses getting to cells by understanding our processes we could develop a good drugs and antibodies and vaccines to start that process so these are our understanding of this process.
we are now using the genetic and recombination technologies develop several vaccine strategies hopefully by using those strategies and immunize individuals we are able to induce the antibody responses able to stop the viral infection so that actually the prime purpose of our current research on campus on the other hand uses cognitive processes we also develop a crucial in illogical testing help the frontline physicians to evaluate the plasma and blood amiri activity so they could use as a surrogate marker to evaluate the potential effectiveness of the plasma infusion that is to treat most severe patient at frontline talking about plasma this is the key word or recently in terms of therapeutic treatment now that process of being used in many cases earlier in treating different kinds of diseases
but,
whether do we know or not this is likely to work according to the latest the situation we have 11 so-called successful cases within 24 hours but is that big enough to support this argument this is a very important area of investigation for this particular carnivals we are not certain whether or to what extent is a effective so that require a systematic and comprehensive research that's why we are providing the support to evaluate the new status of that plasma try to correlate that with the effectiveness of treatment in fact this concept of using plasma to treat infectious diseases back to almost a hundred years ago and when the German scientist ambulant Aran developed the antiserum of plasma against the toughest area so he actually the first winner of normal price in his industry and then and then in medicine but because of his idea and concept develop of equivalent plasma treatment for infectious diseases in fact during the outbreak of many other more infection including Ebola and then highly pathogenic influenza some editors experiment has been conducted in human
but the size and also the conclusive conclusion have not been wished yeah so given the size of the severe infected patients now in China we are have it is unique and then good opportunity to address that in a most a scientific manner so we could reach a firm conclusion based on those important studies professor Jung now we understand more than 10,000 people according to the latest information recovered about the question really is what is the ratio professor there's a crucial issue like this about you know how much a plasma being used can be for the treatment of how many patients or vice versa do we know is there any statistics that
we
have collected whether this is going to be a resource effective this is a really great question because if we depend on those natural reasons resources work will be very limited but at present given what we have practiced over the years for a donor if you are a convalescent you can cover patients you are encouraged to donate plasma blood for the severe for treatment of severe patient for each one donation someone could donate several hundreds of meals and then you could use that and after certain treatments and then of this plasma samples to remove some potential harmful materials and to activate viruses those samples can be infused directly into patients may be with ranging from two hundred to two more meals but as I said those are dependent on the natural resources of convalescent patients and quite limited that's why in our research field we have been collaborating to the partners in Beijing in change and many many other places try to isolate those antibodies from the recover patients so we could use molecular current method and also production facility to manufacturers kilogram we use tons of those antibodies that will overcome the sharpish on its means from convalescent serum on patients there's another thing regarding plasma because we had earlier public health emergencies or accidents when people donate their blood and they have the plasma separated from the blood cells and eventually they have the once again there the rest of the blood coming back to their body just is going to help those who have donated the blood but eventually became a public health accident we remember that we were well are concerning them AIDS patients years ago so a professor Jeong at this critical moment everybody's rushing for solutions how important it is that we take care of different size of the same issue those are really good points we when the immersion happens we tend to be over overly act and then during this roughness we may make some mistakes but we have to be very very vigilant about safety first safety safety safety once we have collected the collagen serum or plasma condensation those who are not will have to be treated properly according to the protocol that has been used in the field for years so safety precautions is is must so given what we have in conducting and knowing all these years the safety procedure has already been in place and I am sure that many of the hospitals and physicians are conducting.
those trials put the safety first on top of the list but you know as you may know call me the 19 is a very infectious disease we have seen it's easily be infectious from one to the other so medical workers at different departments of the hospital I have to protect themselves because they also need to protect their patients because once they are infected they're going to spread it to the others too so how to keep that balance on the one hand you want to make sure there's medical support to the people with long-term disease but on the other hand you want to make sure all the medical workers as well as patients seeking pay is seeking treatment in the hospitals can be saved this is quite a dilemma absolutely I think that this emergency cases in particular we are not understanding or we don't understand fully how this virus translates so viciously so everybody has to be in precaution to prevent themselves and prevent from their patients to be infected this is entirely new viruses to us and we don't know how it is in fact so it is a better for all of us to be to be on guard and to be fully cautious and protect themselves and then to minimize the chance of transmission ,
so I mean it is a added burden to everyone I see particularly in the hospital setting we know professor John that the w-h-o expert team is now in China not only including those coming from whu-oh headquarter but also those from different parts of the world from different countries if you were on that team as a medical worker or as a health expert what do you think are some of the priorities the team should focus on I think you are on the team I would really look at the total health measure that China has put into place and also how effective that measure in containing the epidemic so that's the first priority the second priority was to see how the Chinese physicians and health care providers has been providing those medical care to those unfortunately infected how effective that is and then so so you could learn the lesson from the Chinese experiences third I would look at the research activity and also the the the Chinese spirits how much of those will be applicable to the international community so we could providing better walls and Prevention's of prevention measures to stop this virus to spread into other countries in fact last week in Geneva only show how this research roadmap for this disease including many areas but basically order down to how much we know about this virus transmission what our diagnostic treatment experience the China has gained which could be useful and applicable to the outside China and the development effective vaccines and as well as improve the communication skills because there's so many informations bombarded to the society if you don't know which ones are correct official wishes are simply rumors and then and then lastly we want to encourage the study on the societal impact by the virus on this society on the mental health on our living behaviors so all those things come together we'll be the W shows team to look at I'm sure many of the achievement we made will be applicable to the international community professor John my last question for you now you can look at the numbers confirm the cases are still up even though the growth rate has been slowing down meanwhile you have about a 10,000 recovered already from the very beginning of the outbreak until now what is the current stage if you can share with us your insight some predictions about the overall outbreak and also what does this mean when China which is becoming the epicenter you would think about the world the epicenter of the world of this outbreak what about the other places is this going to continue to the other places now a professor Jeong what's your assessment I mean a prediction for infectious disease is always very very difficult although there's a lot of model floating around giving the numbers that really try to predict situations so it is hard to start with but is it it is it is a it is a is a good to know that the rate of increase has been slowed down a little bit but I wouldn't be too complacent about it because given the number of the infected people in Wuhan at the epicenter of this epidemic and even the number of severe cases in particular given the near hospitals that they built a lot of people need to be transferred the logistic difficulties combined we still have a long way to go before we see the turning point of this epidemic so it has to be fully prepared and in fully vigilant and fully what what as hard as beautiful we could to clay and his disease so there will be quite well before we see the deflection point of this epidemic so the light at the end of the tunnel is still a bit far is that what you're trying to say professor yes we are confident we will win this war against the virus but we have to be well prepared before we get there and then I think combining these tougher measures in terms of Quentin isolation to break down the power transmission rule and also boost up the medical care services to those severely affected in particular by Karunya research on vaccine treatments and then drugs that will eventually put this virus into his own place so hopefully this will come sooner than later professor jeonghwan sheep thank you so much for joining us I learned a lot all the best to you and your team - looking forward to that result you very much
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